Pharmacology III — Medication Dashboard

All meds across 6 topic groups · class-grouped · color-coded · click a class for per-drug detail · flashcard mode
Topic
Drug class group
📊 High-Yield Diagrams · original study schematics · click Diagrams again to hide
High-Yield Pharmacology: Opioids and Muscle Relaxants — study poster
High-yield poster: opioid mechanistic categories & DEA scheduling, MME, routes/onset, the “big three” ADRs, methadone/QT, tramadol, and central vs peripheral muscle relaxants (cyclobenzaprine, dantrolene, tizanidine, metaxalone).
Nephron — Diuretic Sites of Action Glom. PCT Loop diuretics (TAL) Thiazides (DCT) K⁺-sparing / aldosterone (CD) Loops lose Ca²⁺ · Thiazides hold Ca²⁺ · CD agents spare K⁺
Where each diuretic class acts along the tubule.
Cardiac AP — Vaughan-Williams Classes 0 2 3 Class I — Na⁺ (phase 0) Class IV — Ca²⁺ (plateau) Class III — K⁺ (repol., ↑QT) Class II — β-block (SA/AV node) I = Na · II = β · III = K · IV = Ca
Which ion/phase each antiarrhythmic class targets.
RAAS — Where the Drugs Block Angiotensinogen ⊣ renin: Aliskiren Angiotensin I ⊣ ACE: -prils (↑bradykinin→cough) Angiotensin II ⊣ AT1 receptor: -sartans ↑BP · vasoconstriction · aldosterone ARNI = sacubitril (neprilysin inhibitor) + valsartan neprilysin normally degrades BNP/ANP → ARNI preserves them
Each RAAS agent's block point — and why ACEIs cause cough.
Adrenergic Receptors — Targets β1heart, kidney ↑HR/contractility, ↑renin β2lungs, vessels bronchodilation α1vessels, prostate vasoconstriction α2CNS (presynaptic) α2 agonists ↓ central sympathetic outflow (clonidine, methyldopa)
Receptor map for BBs, α-blockers & central agents.
Lipid Handling — Drug Targets Gutcholesterol absorption ⊣ Ezetimibe ⊣ Bile acid sequestrants Liver — HMG-CoAcholesterol synthesis ⊣ Statins (rate-limiting step) ⊣ Bempedoic acid LDL receptor PCSK9 inhibitors / inclisiran (↑ LDLR recycling → ↓ LDL) Triglycerides / VLDLlipoprotein lipase ↓ Fibrates, Niacin, Omega-3 Statins = LDL ↓↓ & mortality benefit · Fibrates/omega-3 = TG
Where each lipid drug works — LDL vs triglyceride agents.
🎯 MSK Med Traps — 40 nuance questions · osteoporosis · gout · NSAIDs/analgesics · opioids · muscle relaxants · click an answer for instant feedback